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Supply Mirabegron with low price for sale CAS NO.223673-61-8
- Min.Order: 1 Gram
- Payment Terms: L/C,T/T,Other
- Product Details
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- Mirabegron for sale
- Supply Mirabegron
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Quick Details
- ProName: Supply Mirabegron with low price for s...
- CasNo: 223673-61-8
- Molecular Formula: C21H24N4O2S
- Appearance: White to off-white powder
- Application: Pharmaceutical products
- DeliveryTime: Goods in stock
- PackAge: 1KG; 10KG; 25KG
- Port: Any port in China
- ProductionCapacity: 200 Kilogram/Month
- Purity: 99%
- Transportation: by air, by courier or by sea
- LimitNum: 1 Gram
- Related Substances: not more than 1.0%
- Heavy Metal: 20ppm
- Valid Period: two years
Superiority
Supply Mirabegron with low price for sale
Mirabillon relaxes and increases the stability of the detrusor by acting on the 3 receptor. Three receptor subtypes (1, B2, and 3) were found in human detrusor cells and epithelial cells of the urethra. MRNAChemicalbook of the 3 receptor was mainly expressed in human detrusor smooth muscle cells, accounting for 97% of the receptor mRNA in bladder tissues. The expression of receptor mRNA and the function of its signaling pathway suggest that 3 receptor plays a pivotal role in normal and diseased bladders.
Details
Mirabelone is a line drug in the treatment of bladder hyperactivity with obvious curative effect, clear mechanism of action and little side effect.
And now its API synthesis yield is very low, cost, product impurities, purification is difficult, so the synthesis of mira veron and each steps of process optimization research is particularly important, p-nitrophenyl) and (R) - styrene oxide as raw materials via ring-opening reaction, reduction reaction and condensation, the product get mira veron.
The synthesis process was improved and optimized, and the optimum conditions for each step were determined by several experiments, the optimum molar ratio was 1:1.2, the solvent to raw material mass ratio was 10:1, the reaction time was 5h, and mirabillon and its key intermediates were confirmed by analysis and test. The reaction route has the advantages of low production cost, mild reaction, simple operation and high total yield. The rice was synthesized by analysis
The main impurity of Labelon is the removal of hydroxyl mirabelon.